Empower your annotation practice with interactive and user-friendly interface!
GNX-AI allow users to interpretate genetic mutations in oncology field, enhancing variant
annotation and visualization.
Understanding how variant annotation
analysis perform
Login and Upload VCF file
GNX-AI offers a secure login with 2-step verification (username and password) and a quick upload of VCF files.
To upload VCF, click on “UPLOAD FILE”, selecting the file to be uploaded and then analysed.
To complete this step, click on “Upload”: file progress upload will be displayed by a loading bar.
Launch Analysis
The analysis step is optimized for different sequencing Input file data (WES, WGS, Panels) and for somatic variant analysis.
Before launch analysis following actions are recommended:
Samples information insertion, to obtain the most comprehensive analysis possible.
Phenotype input, to focus the analysis on a specific phenotype criterion.
Annotation and Variants visualization
GNX-AI offers an intuitive, streamlined variant browsing interface with an interactive table.
The annotation process will return the most useful variant information, kept from several ACMG recommended scientific databases.
Annotations in the variant dashboard can be applied to the filter, and variants can be sorted according to any column.
The users could select the variants of interest using a specific tag section.
Reporting
GNX-AI offers users the option to generate a report of specific selected variants in PDF format, clicking on “Result Download”.
Benefits
Filtering Customized
GNX-AI offers a powerful variant filter process in order to visualize the data according to the user’s requirements.
Multiple views
GNX-AI offers a powerful variant filter process in order to visualize the data according to the user’s requirements.
Customized Report
Reports are fully customizable to include only the flagged variants of interest with the possibility to add comments and notes.
Rapid phenotype-genotype correlation
Full compliance with ACMG guidelines for sequence variant interpretation
Fast upload of VCF files
Key Features
CE-IVDR compliance for annotation & visualization of NGS data
Connects with main gene variant databases (ClinVar, DBSpn, CIVIC, etc.)
Freedom to choose how to select variants, without pre-imposed filtering.
Quality: Regulation Certification EU -IVDR
GNX-AI is a CE IVDR-certified and ISO27001-compliant platform allowing fast and accurate variant discovery, annotation, and visualization of NGS data for whole genomes, exomes, and gene panels.
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Company Info
P.IVA: 09279340153
Via Privata Cesare Battisti, 1
20122, Milano
Contacts
Tel. +39 0371.1921800
Fax +39 0371.610029
info@gnx-ai.com