Login and Upload VCF file

GNX-AI offers a secure login with 2-step verification (username ad password) and a quick upload of VCF files.

To upload VCF, click on “UPLOAD FILE”, selecting the file to be uploaded and then analysed.

To complete this step, click on “Upload”: file progress upload will be displayed by a loading bar.

To complete this step, click on “Upload”: file progress upload will be displayed by a loading bar.

 Launch Analysis

The analysis step is optimized for different sequencing Input file data (WES, WGS, Panels) and for somatic variant analysis. 

Before launch analysis following actions are recommended: 

- ​samples information (ID, origin and ethnicity, gender and age) insertion, to obtain the most comprehensive analysis possible.

- ​phenotype input, to focus the analysis on a specific phenotype criterion.

Annotation and Variants visualization

GNX-AI offers an intuitive, streamlined variant browsing interface with an interactive table.

The annotation process will return the most useful variant information, kept from several ACMG recommended scientific databases.

Annotations in the variant dashboard can be applied to the filter, and variants can be sorted according to any column.

The users could select the variants of interest using a specific tag section.

Reporting

GNX-AI offers users the option to generate a report of specific selected variants in PDF format, clicking on “Result Download”.