Empower your annotation practice with interactive and user-friendly interface!  


GNX-AI allow users to interpretate genetic mutations in oncology field, enhancing variant annotation and visualization.

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Understanding how variant annotation 

analysis perform


 

Login and Upload VCF file


GNX-AI offers a secure login with 2-step verification (username ad password) and a quick upload of VCF files.

To upload VCF, click on “UPLOAD FILE”, selecting the file to be uploaded and then analysed.

To complete this step, click on “Upload”: file progress upload will be displayed by a loading bar.


 Launch Analysis


The analysis step is optimized for different sequencing Input file data (WES, WGS, Panels) and for somatic variant analysis. 

Before launch analysis following actions are recommended: 

​Samples information insertion, to obtain the most comprehensive analysis possible.

           ​Phenotype input, to focus the analysis on a specific phenotype criterion.

Annotation and Variants visualization


GNX-AI offers an intuitive, streamlined variant browsing interface with an interactive table.

The annotation process will return the most useful variant information, kept from several ACMG recommended scientific databases.

Annotations in the variant dashboard can be applied to the filter, and variants can be sorted according to any column.

The users could select the variants of interest using a specific tag section.


Reporting


GNX-AI offers users the option to generate a report of specific selected variants in PDF format, clicking on “Result Download”.




 

Benefits


  Filtering Customized

GNX-AI offers a powerful variant filter process in order to visualize the data according to the user’s requirements. 


Multiple views

 GNX-AI offers a powerful variant filter process in order to visualize the data according to the user’s requirements.

 

 Customized Report

Reports are fully customizable to include only the flagged variants of interest with the possibility to add comments and notes.

Rapid phenotype-genotype correlation

Full compliance with ACMG guidelines for sequence variant interpretation

Fast upload of VCF files

Key Features

  CE-IVDR compliance for annotation & visualization of NGS data

Connects with main gene variant databases (ClinVar, DBSpn, CIVIC, etc.)

Freedom to choose how to select variants, without pre-imposed filtering.

Quality: Regulation Certification EU -IVDR  

 

GNX-AI is a CE IVDR-certified and ISO27001-compliant platform allowing fast and accurate variant discovery, annotation, and visualization of NGS data for whole genomes, exomes, and gene panels.

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Company Info

P.IVA: 09279340153

Via Privata Cesare Battisti, 1  

20122, Milano

Contacts

Tel. +39 0371.1921800 

Fax +39 0371.610029

info@gnx-ai.com